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CURRICULUM VITAE

Address :    PO Box 100, 1 Bungtown Road
                     Cold Spring Harbor Laboratory
                     NY 11724, U.S.A.
Phone :       +1 (516) 367-8866.
Fax :           +1 (516) 367-8461.
E-Mail :     ioshikhe@cshl.org

CURRENT POSITION :

1997 - now       Postdoctoral fellow in Cold Spring Harbor Laboratory.
                           Supervisor - Dr. M.Q. Zhang.
                           Subject : Sequence analysis of eukaryotic promoters, eukaryotic promoter recognition.
                           Development, management and analysis of eukaryotic promoter DNA databases.

EDUCATION :

1992 - 1997     The Weizmann Institute of Science (Rehovot, Israel),
                          Department of Structural Biology.
                          Ph.D. degree under the supervision of Prof. E.N. Trifonov & Dr. L. Ulanovsky.
                          Subject : Recognition of subtle patterns in DNA sequences.
                          1. Development, management and analysis of nucleosome DNA sequence database.
                          Extraction of common nucleosome DNA sequence pattern by multiple sequence alignment,
                          resonance and linguistic analysis. Nucleosome structure and positioning.
                          2. Calculation of suboptimal single-stranded DNA folding and evaluation of its influence on
                          efficiency of DNA sequencing by modular primers.
                          The work included development of original algorithms and software.

1978 - 1983      State University in Dushanbe (USSR),
                          Department of Physics (Theoretical Physics) (MS degree).
                          Thesis : Averaged description of biological macromolecule in solution.

Additional studies :

1998,1997         Cold Spring Harbor Laboratory,
                          Computational Genomics course.

1995                 'Telran' company (Nes-Ziona, Israel).
                          UNIX system administration course.

1987 - 1988     Correspondence studies under the supervision of Prof. M.D. Frank-Kamenetsky
                         (Institute of Molecular Genetics, Moscow).
                         Subject : Thermodynamics of B - to Z - DNA transition.

COMPUTER EXPERIENCE :

Programming languages :   C, Perl, Turbo-Pascal, Fortran, Basic, HTML.
Environment :                      UNIX (Sun, Digital, IRIX, AIX), NT, Windows, MS-DOS, OS.
Computers :                         Sun, Silicon Graphics, Macintosh, PC-NT, PC, MF.

WORKING EXPERIENCE :

1990 - 1994    Research fellow at the College of Judea and Samaria (Ariel, Israel).
                        Work subject : Creation of nucleosomal DNA sequence database.
                         Extraction of nucleosomal  DNA sequence pattern by multiple sequence alignment.

1989                Senior research fellow (analyst, programmer) at
                        "Ravshan" Scientific-Technical Center (Dushanbe).
                        Work subjects :
                        1. Development of a software package for optimum planning of a schedule for airplane flights.
                        2. Adjusting of software package for mathematical modeling of turbulent mixing of gas streams
                           with suspended admixtures in chemical reactors.

1986 - 1989   Research fellow (analyst, programmer) at the State University (Dushanbe).
                        Work subjects :
                        1. Computer mathematical modeling of behavior and calculation of seismoresistance of
                            electrical equipment while affecting by earthquake. Development of a software package.
                        2. Development of software package for optimum planning of a non-stop manufacture for
                            oil-processing industry.

1984 - 1986   Programmer (positions: engineer, senior engineer) at the
                        Computer Center of the Ministry of Building, Dushanbe.

1983 - 1984   Senior lab assistant at the Medical Institute, Dushanbe.